Motif ID: MEF2{A,B,C,D}.p2

Z-value: 2.288


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEF2BNB-MEF2Bchr19_-_193029160.581.1e-20Click!
MEF2Dchr1_-_1564603900.573.9e-20Click!
MEF2Bchr19_-_19281090,
chr19_-_19281062
0.433.6e-11Click!
MEF2Cchr5_-_881998680.371.2e-08Click!
MEF2Achr15_+_1001062140.305.9e-06Click!


Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_88450601 85.166 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr9_+_139871954 52.106 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr5_-_42811959 48.647 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr13_-_45048436 47.509 NM_001243798
TSC22D1
TSC22 domain family, member 1
chr9_+_139872014 47.143 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr12_+_52445185 45.517 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr12_-_45269340 43.145 NM_001145109
NELL2
NEL-like 2 (chicken)
chr12_-_9268440 40.265 A2M
alpha-2-macroglobulin
chr12_-_16759939 39.524 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_27472188 39.468 CLU
clusterin
chr14_-_21493858 38.581 NDRG2
NDRG family member 2
chr12_-_111358353 37.469 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr14_-_21493910 37.200 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr17_+_37821598 35.602 NM_003673
TCAP
titin-cap (telethonin)
chr1_+_160085519 32.461 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr20_+_44657812 31.925 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_-_211168315 31.864 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr20_+_44657858 31.810 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr1_+_92632608 31.456 NM_015237
KIAA1107
KIAA1107
chr14_-_103989195 30.898 NM_001823
CKB
creatine kinase, brain
chr5_+_150399980 30.863 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr2_+_233498206 29.922 NM_025202
EFHD1
EF-hand domain family, member D1
chr19_-_36643770 29.405 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr8_-_33457491 28.687 DUSP26
dual specificity phosphatase 26 (putative)
chr14_-_103989112 28.425 CKB
creatine kinase, brain
chr6_+_7108864 28.087 RREB1
ras responsive element binding protein 1
chr18_-_3219986 27.955 NM_003803
NM_019856
MYOM1

myomesin 1, 185kDa

chr19_+_12203077 27.926 ZNF788
zinc finger family member 788
chr5_+_150400132 27.247 GPX3
glutathione peroxidase 3 (plasma)
chr1_-_230849863 27.180 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_116311161 26.580 CASQ2
calsequestrin 2 (cardiac muscle)
chr1_-_116311398 26.523 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr1_-_116311330 25.689 CASQ2
calsequestrin 2 (cardiac muscle)
chr19_-_45822841 25.655 CKM
creatine kinase, muscle
chr16_+_84328400 25.645 NM_021197
WFDC1
WAP four-disulfide core domain 1
chr7_+_30951414 25.567 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr8_-_33457279 25.138 DUSP26
dual specificity phosphatase 26 (putative)
chr11_-_19223516 24.940 NM_001127656
NM_003476
CSRP3

cysteine and glycine-rich protein 3 (cardiac LIM protein)

chr12_-_9268475 24.907 A2M
alpha-2-macroglobulin
chr1_-_57045129 24.374 PPAP2B
phosphatidic acid phosphatase type 2B
chr14_-_103988829 24.130 CKB
creatine kinase, brain
chr12_-_16760935 24.128 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr2_+_20646831 24.096 NM_004040
RHOB
ras homolog gene family, member B
chr12_+_119616594 23.704 NM_014365
HSPB8
heat shock 22kDa protein 8
chr5_+_161274939 23.559 NM_001127644
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_-_27115935 23.542 STMN4
stathmin-like 4
chr20_+_44035203 22.762 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr13_-_45011389 22.579 NM_001243797
TSC22D1
TSC22 domain family, member 1
chr17_+_7554711 21.979 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr7_-_37488554 21.866 NM_014800
ELMO1
engulfment and cell motility 1
chr8_+_27631902 21.801 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr8_-_110661007 21.754 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr4_-_88450243 21.680 SPARCL1
SPARC-like 1 (hevin)
chr10_-_75401199 21.359 MYOZ1
myozenin 1
chr12_-_16758312 21.355 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_64023444 21.185


chr6_-_169653922 21.001 THBS2
thrombospondin 2
chr22_+_22569155 20.918


chr13_-_45011059 20.555 NM_006022
TSC22D1
TSC22 domain family, member 1
chr3_-_195310770 20.553 APOD
apolipoprotein D
chr15_+_68908878 20.435 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chr14_-_101036130 20.404 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr10_-_75401492 20.286 NM_021245
MYOZ1
myozenin 1
chr17_+_43971655 20.026 NM_001123066
NM_001123067
NM_001203251
NM_001203252
NM_005910
NM_016834
NM_016835
NM_016841
MAPT







microtubule-associated protein tau







chr8_+_80523304 19.952 STMN2
stathmin-like 2
chr7_-_37488408 19.776 ELMO1
engulfment and cell motility 1
chr5_+_161275185 19.756 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_-_27115897 19.647 NM_030795
STMN4
stathmin-like 4
chr18_-_3219846 19.598 MYOM1
myomesin 1, 185kDa
chr11_+_60260250 19.283 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr4_-_122302112 19.063 NM_198179
QRFPR
pyroglutamylated RFamide peptide receptor
chr17_+_1665306 18.956 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_+_111717585 18.466 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr14_-_107131217 18.314 IGHA1
immunoglobulin heavy constant alpha 1
chrX_-_138287180 18.116 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr1_-_183274008 17.454 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr9_+_124048396 17.300 GSN
gelsolin
chr17_+_1665342 17.207 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr4_+_113970784 17.160 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr19_+_16607181 17.113 NM_032207
C19orf44
chromosome 19 open reading frame 44
chr12_-_9268513 16.898 A2M
alpha-2-macroglobulin
chr17_+_1665281 16.815 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_-_57045235 16.656 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr8_+_80523351 16.582 STMN2
stathmin-like 2
chr17_+_1665233 16.564 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_-_175712276 16.554 NM_001206602
CHN1
chimerin (chimaerin) 1
chr5_-_16509106 16.501 NM_019000
FAM134B
family with sequence similarity 134, member B
chr19_-_50666279 16.433 NM_152358
IZUMO2
IZUMO family member 2
chr4_-_76944585 16.424 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr7_-_151216951 16.282 NM_005614
RHEB
Ras homolog enriched in brain
chr7_-_113559048 16.100 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr18_+_29171729 15.925 NM_000371
TTR
transthyretin
chr2_-_89292396 15.770 IGKC
immunoglobulin kappa constant
chr2_-_211179765 15.719 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr9_+_103947316 15.657 NM_017753
LPPR1
lipid phosphate phosphatase-related protein type 1
chr1_-_230849847 15.386 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr19_+_3933100 15.340 NM_170678
ITGB1BP3
integrin beta 1 binding protein 3
chr3_+_138067678 15.279 NM_001252092
MRAS
muscle RAS oncogene homolog
chr15_+_73976720 15.167 CD276
CD276 molecule
chr9_+_100263818 15.125 NM_003275
TMOD1
tropomodulin 1
chr1_-_230850335 15.003 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_138067444 14.983 NM_001085049
NM_001252093
MRAS

muscle RAS oncogene homolog

chr12_-_9268522 14.956 NM_000014
A2M
alpha-2-macroglobulin
chr12_-_45270157 14.776 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr1_-_57044980 14.758 PPAP2B
phosphatidic acid phosphatase type 2B
chr4_-_87028805 14.640 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr1_-_153029987 14.600 NM_005988
SPRR2A
small proline-rich protein 2A
chr19_-_21512148 14.544 NM_021269
ZNF708
zinc finger protein 708
chr8_-_27472298 14.499 NM_001831
CLU
clusterin
chr12_-_16759531 14.426 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_+_80899458 14.333 ZMIZ1
zinc finger, MIZ-type containing 1
chr1_+_15990300 14.297


chr4_+_70861647 14.290 NM_001009181
NM_003154
STATH

statherin

chr12_+_79257772 14.288 NM_001135805
SYT1
synaptotagmin I
chr4_-_80329354 14.285 NM_033214
GK2
glycerol kinase 2
chr17_+_7184978 14.222 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr12_-_16759430 14.137 LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_+_32856650 14.087 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr6_+_7590405 13.991 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr14_-_23877480 13.915 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr11_-_18034688 13.837 SERGEF
secretion regulating guanine nucleotide exchange factor
chr19_-_48614013 13.705 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr13_-_36429798 13.689 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr9_+_105757592 13.664 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr7_+_23286390 13.536 GPNMB
glycoprotein (transmembrane) nmb
chr6_+_27806322 13.525 NM_003520
HIST1H2BN
histone cluster 1, H2bn
chr22_-_37215516 13.514 NM_002854
PVALB
parvalbumin
chr15_+_42651697 13.276 NM_000070
NM_024344
NM_173087
CAPN3


calpain 3, (p94)


chr1_+_13911966 13.220 NM_001006624
NM_001006625
PDPN

podoplanin

chr2_+_173686314 13.214 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_-_56160604 13.190 NM_006213
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr6_-_27806116 13.173 NM_003510
HIST1H2AK
histone cluster 1, H2ak
chr10_+_88428263 13.105 NM_001080116
NM_001080114
NM_001080115
NM_001171611
NM_007078
LDB3




LIM domain binding 3




chr2_+_170366211 13.057 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr4_-_39640461 13.051 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr11_+_46958228 12.888 NM_001003676
NM_001003677
NM_001003678
NM_024113
C11orf49



chromosome 11 open reading frame 49



chr5_-_149535138 12.846 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr16_-_31439650 12.750 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr5_-_115910406 12.736 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr9_-_34691135 12.647 NM_006274
CCL19
chemokine (C-C motif) ligand 19
chr12_+_69201979 12.545 MDM2
Mdm2 p53 binding protein homolog (mouse)
chr11_-_128894008 12.433 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr11_-_47374221 12.431 NM_000256
MYBPC3
myosin binding protein C, cardiac
chr1_+_151032880 12.378 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_151032866 12.308 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr19_-_55668956 12.274 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr12_-_16759733 12.254 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_34891262 12.141 NM_001033580
NM_001163735
NM_025109
MYO19


myosin XIX


chr13_-_25497054 12.059 NM_018451
CENPJ
centromere protein J
chr22_-_38577692 12.044 NM_001004426
NM_003560
NM_001199562
PLA2G6


phospholipase A2, group VI (cytosolic, calcium-independent)


chr1_+_183605207 11.984 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr12_+_81101407 11.980 NM_002469
MYF6
myogenic factor 6 (herculin)
chr10_-_14879967 11.883 NM_001029954
CDNF
cerebral dopamine neurotrophic factor
chr11_-_18034491 11.839 NM_012139
SERGEF
secretion regulating guanine nucleotide exchange factor
chr19_-_20748540 11.732 NM_001159293
ZNF737
zinc finger protein 737
chr1_+_65730423 11.647 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr10_-_45474210 11.605 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr6_-_6007097 11.414 NRN1
neuritin 1
chr17_-_2966900 11.373 NM_014566
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr4_-_186877413 11.369 SORBS2
sorbin and SH3 domain containing 2
chrX_+_64708614 11.181 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr15_+_41576150 11.160 OIP5-AS1
OIP5 antisense RNA 1 (non-protein coding)
chr1_-_201390845 11.156 NM_003281
TNNI1
troponin I type 1 (skeletal, slow)
chr5_+_53751430 11.102 NM_006308
HSPB3
heat shock 27kDa protein 3
chr19_+_18062110 11.015 NM_002248
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr9_+_21440452 10.989 NM_024013
IFNA1
interferon, alpha 1
chr9_-_21228132 10.970 NM_021268
IFNA17
interferon, alpha 17
chr15_+_93443418 10.837 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr7_-_99680358 10.820 ZNF3
zinc finger protein 3
chrX_-_21776158 10.767 NM_014332
SMPX
small muscle protein, X-linked
chr1_+_160160284 10.656 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr11_+_1860232 10.646 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr4_+_41362750 10.588 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr5_+_140749830 10.587 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr1_+_151032683 10.579 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_+_23286386 10.562 GPNMB
glycoprotein (transmembrane) nmb
chr4_-_46995440 10.505 NM_001204266
NM_001204267
GABRA4

gamma-aminobutyric acid (GABA) A receptor, alpha 4

chr14_+_95078713 10.501 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr8_-_6856678 10.478 NM_004084
NM_001042500
DEFA1
DEFA1B
defensin, alpha 1
defensin, alpha 1B
chr12_-_371994 10.476 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr12_-_45270071 10.449 NELL2
NEL-like 2 (chicken)
chr9_+_33290536 10.327 NFX1
nuclear transcription factor, X-box binding 1
chr3_-_114343052 10.302 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_33661392 10.202 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_-_37488894 10.196 NM_001206480
ELMO1
engulfment and cell motility 1
chr10_-_69597768 10.181 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr4_-_140098236 10.175


chr10_+_88428167 10.070 NM_001171610
LDB3
LIM domain binding 3
chr1_-_115238091 10.054 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr5_-_142077508 10.011 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr3_+_9691184 9.920 MTMR14
myotubularin related protein 14
chr19_-_54311958 9.877 NM_033297
NLRP12
NLR family, pyrin domain containing 12
chr10_-_75415748 9.860 NM_001114133
SYNPO2L
synaptopodin 2-like
chr5_+_140729723 9.854 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr7_-_83278478 9.752 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_-_153085963 9.738 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr2_-_228497801 9.735 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr11_-_62457001 9.686 LRRN4CL
LRRN4 C-terminal like
chr1_-_115323262 9.649 NM_001102396
NM_025073
SIKE1

suppressor of IKBKE 1

chr1_-_201346804 9.596 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)




Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 1.42e-10 GO:0032501 multicellular organismal process
3.45 4.15e-08 GO:0003012 muscle system process
2.03 3.41e-07 GO:0006955 immune response
3.35 1.16e-06 GO:0006936 muscle contraction
1.52 2.68e-06 GO:0065008 regulation of biological quality
6.50 4.10e-06 GO:0030049 muscle filament sliding
6.50 4.10e-06 GO:0033275 actin-myosin filament sliding
1.71 4.28e-06 GO:0002376 immune system process
6.33 6.39e-06 GO:0070252 actin-mediated cell contraction
2.04 1.17e-05 GO:0048878 chemical homeostasis
2.54 5.87e-05 GO:0061061 muscle structure development
1.39 6.98e-05 GO:0048731 system development
1.34 9.36e-05 GO:0007275 multicellular organismal development
1.32 1.44e-04 GO:0032502 developmental process
1.80 1.74e-04 GO:0006952 defense response
1.35 1.93e-04 GO:0048856 anatomical structure development
2.79 2.21e-04 GO:0007517 muscle organ development
1.82 2.63e-04 GO:0007267 cell-cell signaling
1.60 4.18e-04 GO:0051239 regulation of multicellular organismal process
1.31 4.67e-04 GO:0023052 signaling
4.72 6.16e-04 GO:0030048 actin filament-based movement
2.39 6.79e-04 GO:0055065 metal ion homeostasis
1.72 1.03e-03 GO:0042592 homeostatic process
1.48 1.05e-03 GO:0003008 system process
2.04 1.34e-03 GO:0055082 cellular chemical homeostasis
2.67 1.43e-03 GO:0006874 cellular calcium ion homeostasis
1.76 1.94e-03 GO:0007155 cell adhesion
1.76 1.94e-03 GO:0022610 biological adhesion
2.35 2.12e-03 GO:0006875 cellular metal ion homeostasis
1.64 2.18e-03 GO:0007154 cell communication
2.20 2.24e-03 GO:0055080 cation homeostasis
1.99 2.38e-03 GO:0050801 ion homeostasis
2.03 2.52e-03 GO:0006873 cellular ion homeostasis
3.38 2.66e-03 GO:0045765 regulation of angiogenesis
2.59 2.92e-03 GO:0055074 calcium ion homeostasis
2.59 2.92e-03 GO:0072503 cellular divalent inorganic cation homeostasis
5.20 3.06e-03 GO:0006941 striated muscle contraction
2.24 3.45e-03 GO:0030003 cellular cation homeostasis
1.15 3.56e-03 GO:0065007 biological regulation
1.43 3.84e-03 GO:0048513 organ development
1.75 5.96e-03 GO:0002682 regulation of immune system process
4.01 6.09e-03 GO:0051494 negative regulation of cytoskeleton organization
2.49 6.42e-03 GO:0072507 divalent inorganic cation homeostasis
1.64 7.21e-03 GO:0050793 regulation of developmental process
2.13 7.22e-03 GO:0044057 regulation of system process
2.13 9.15e-03 GO:0031347 regulation of defense response
3.24 9.32e-03 GO:0007586 digestion
1.62 1.72e-02 GO:0009611 response to wounding
4.48 1.80e-02 GO:0031333 negative regulation of protein complex assembly
1.82 1.85e-02 GO:0019725 cellular homeostasis
3.42 2.61e-02 GO:0034754 cellular hormone metabolic process
1.36 2.92e-02 GO:0048869 cellular developmental process
2.27 3.14e-02 GO:0008202 steroid metabolic process
1.37 3.40e-02 GO:0030154 cell differentiation
6.11 4.93e-02 GO:0030239 myofibril assembly

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.15 3.76e-15 GO:0044421 extracellular region part
2.24 7.22e-13 GO:0005615 extracellular space
4.42 1.14e-10 GO:0030016 myofibril
4.30 1.15e-10 GO:0043292 contractile fiber
4.26 1.84e-09 GO:0044449 contractile fiber part
1.60 2.10e-09 GO:0005576 extracellular region
1.74 5.16e-08 GO:0031226 intrinsic to plasma membrane
1.75 6.00e-08 GO:0005887 integral to plasma membrane
4.09 2.74e-07 GO:0030017 sarcomere
1.50 6.06e-07 GO:0044459 plasma membrane part
8.91 7.64e-06 GO:0005859 muscle myosin complex
8.91 7.64e-06 GO:0032982 myosin filament
8.02 2.88e-05 GO:0016460 myosin II complex
3.76 2.12e-03 GO:0016459 myosin complex
1.53 2.84e-03 GO:0000267 cell fraction
2.02 1.33e-02 GO:0015629 actin cytoskeleton
1.56 1.50e-02 GO:0005626 insoluble fraction
1.87 2.03e-02 GO:0031012 extracellular matrix
1.20 3.09e-02 GO:0071944 cell periphery
1.20 3.38e-02 GO:0005886 plasma membrane
3.12 3.94e-02 GO:0042383 sarcolemma

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.60 1.16e-05 GO:0008307 structural constituent of muscle
4.40 9.69e-04 GO:0042379 chemokine receptor binding
4.53 1.59e-03 GO:0008009 chemokine activity
2.48 1.78e-03 GO:0005125 cytokine activity
3.88 2.35e-03 GO:0005319 lipid transporter activity
1.56 3.96e-03 GO:0005102 receptor binding
2.33 3.36e-02 GO:0001664 G-protein-coupled receptor binding